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By G. Bettendorf (auth.), R. Rolland, R. F. Harrison, J. Bonnar, W. Thompson (eds.)

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Additional info for Advances in Fertility Control and the Treatment of Sterility: The Proceedings of a Special Symposium held at the XIth World Congress on Fertility and Sterility, Dublin, June 1983

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Thorner, M. , Perryman, R. , Rogol, A. , et al. (1981). Rapid changes of prolactinoma volume after withdrawal and reinstitution of bromocriptine. J. Clin. Endocrinol. , 53, 480 26. Vaidya, R. , Allorkar, S. D. and Rege, N. R. (1978). Normalization of visual fields following bromocriptine treatment in hyperprolactinemic patients with visual field constriction. Fertil. , 29, 632 27. , Andersen, T. and Karle, A. (1982). Size reduction of extrasellar pituitary tumors during bromocriptine treatment: Quantitation of effect on different types of tumors.

No increase in the number of endometrial tumours was observed in the lisuride studies. In these as well as in other studies, where the development of pituitary tumours was prevented by treatment with lisuride the life-span of the animals was increased. Extensive studies in rodents and monkeys failed to give any evidence of a teratogenic effect; lisuride was embryotoxic only at doses where also some of the adult animals died. The compound crosses the blood-placenta barrier and the blood-brain barrier and seems to achieve higher levels in brain areas with larger numbers of dopamine receptors.

The pill is a topical subject. In my office at home, in the space of a few months, photocopies of articles written both 'for' but slightly more often 'against' the pill and other birth-control methods that have appeared in the national and local press and women's magazines have produced a pile, inches high. To read some of the more sensational articles gives me cause to wonder whether the writer has discovered new methods, since they often do not sound like those used by the vast majority of people that I deal with; but they are.

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